The mounting research regarding the use of PRP for the improvement of fertility in men has been mounting, but there have been no studies regarding the use of PRP for the restoration of size in the testicle. When men take testosterone replacement therapy, and sometime with age, there can be a resulting atrophy of the testicles with a decrease in both size and sperm count.

We will be conducting an IRB-approved clinical trial to evaluate this idea.

If you are interested in participating in this study or in following the results thereof, please tell us how to stay in contact…

Basran, Satvir S., Fausto Negri, Ashkan P. Langroudi, et al. “The Effect of Intratesticular Platelet-Rich Plasma Injection on Sperm Retrieval Rates in Non-Obstructive Azoospermia Male after Failed Testicular Sperm Extraction: An Inception Cohort.” The World Journal of Men’s Health, ahead of print, January 1, 2026. https://doi.org/10.5534/wjmh.250281.
Fazli, Faezeh, Hossein Torkashvand, Ali Reza Soltanian, Ali Babalhavaeji, Hanieh Olomi, and Shamim Pilehvari. “Effects of Testicular Platelet-Rich Plasma (PRP) Injection on Sperm Parameters in Men with Severe Oligoasthenoteratozoospermia (OAT): A Clinical Evaluation.” International Journal of Fertility and Sterility 18, no. Suppl 1 (2024): 71–76. https://doi.org/10.22074/ijfs.2024.2011066.1535.

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*This website is intended solely as professional education for licensed healthcare providers. It is not medical advice, not patient-directed advertising, and not an offer to treat any individual. Nothing here should be used by a member of the public to diagnose or treat any condition; patients should consult a qualified, licensed physician about their own care. The procedures and platelet-rich plasma (PRP) applications discussed are investigational and/or off-label. They have not been evaluated or approved by the U.S. Food and Drug *Administration (FDA) for the uses described, and the FDA has not approved PRP or these procedures to diagnose, treat, cure, or prevent any disease: PRP is a blood product that belongs to the patient, not a drug, and is not regulated by the FDA; also the FDA regulates drugs and devices, not procedures. References to the O-Shot®, P-Shot® (Priapus Shot®), Clitoxin®, Vampire Facial®, Vampire Facelift®, and other trademarked procedures describe training methods and clinical approaches; they do not imply FDA clearance or guaranteed outcomes.

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