Research Supporting or Sponsored by the Cellular Medicine Association

Clitoxin® Research

Landmark study<-

More supporting research<=

O-Shot® (Orgasm Shot®) research

• The O-Shot® procedure for female sexual dysfunction+
• The O-Shot® procedure for lichen sclerosus (symptoms and dermatopathology improved)+
• The O-Shot® procedure to improve the results of surgery for the phimosis of the clitoral hood seen with lichen sclerosus+
• The O-Shot procedure for lichen sclerosus (symptoms and dermatopathology improved)+
The O-Shot® procedure both for female sexual dysfunction and for urinary incontinence+

Vampire Wing Lift® Research

Paola Aguilar, Barbara Hersant, Mounia Sid, Ahmed-Mezi, Romain Bosc, Luciano Vidal, and Jean Paul Meningaud: Novel technique of vulvo-vaginal rejuvenation by lipofilling and injection of combined platelet-rich-plasma and hyaluronic acid: a case-report. SpringerPlus20165:1184

Before and after photos of the Vampire Wing Lift® (click)<–

Neto JB, O-Shot®: O-Shot: Platelet Rich Plasma in Intimate Female Treatment – oshot-platelets-rich-plasma-in-intimate-female-treatment-2167-0420-1000395

Priapus Shot® (P-Shot®) Research

The P-Shot® procedure for Peyronie’s disease
The P-Shot® procedure for penis growth
The P-Shot® procedure for BXO (lichen sclerosus of the foreskin)
More research<=

Priapus Toxin® Research

Abdelrahman, Islam Fathy Soliman, Amr Abdel Raheem, Yaser Elkhiat, Abdelrahman A. Aburahma, Tarek Abdel-Raheem, and Hussein Ghanem. “Safety and Efficacy of Botulinum Neurotoxin in the Treatment of Erectile Dysfunction Refractory to Phosphodiesterase Inhibitors: Results of a Randomized Controlled Trial.” Andrology 10, no. 2 (2022): 254–61. https://doi.org/10.1111/andr.13104.
El-Shaer, Waleed, Hussein Ghanem, Tamer Diab, Ahmed Abo-Taleb, and Wael Kandeel. “Intra-Cavernous Injection of BOTOX® (50 and 100 Units) for Treatment of Vasculogenic Erectile Dysfunction: Randomized Controlled Trial.” Andrology 9, no. 4 (2021): 1166–75. https://doi.org/10.1111/andr.13010.
Giuliano, Francois, Pierre Denys, and Charles Joussain. “Effectiveness and Safety of Intracavernosal IncobotulinumtoxinA (Xeomin®) 100 U as an Add-on Therapy to Standard Pharmacological Treatment for Difficult-to-Treat Erectile Dysfunction: A Case Series.” Toxins 14, no. 4 (2022): 286. https://doi.org/10.3390/toxins14040286.
Giuliano, François, Pierre Denys, and Charles Joussain. “Safety and Effectiveness of Repeated Botulinum Toxin A Intracavernosal Injections in Men with Erectile Dysfunction Unresponsive to Approved Pharmacological Treatments: Real-World Observational Data.” Toxins 15, no. 6 (2023): 382. https://doi.org/10.3390/toxins15060382.
Giuliano, Francois, Charles Joussain, and Pierre Denys. “Safety and Efficacy of Intracavernosal Injections of AbobotulinumtoxinA (Dysport®) as Add-on Therapy to Phosphosdiesterase Type 5 Inhibitors or Prostaglandin E1 for Erectile Dysfunction—Case Studies.” Toxins 11, no. 5 (2019): 283. https://doi.org/10.3390/toxins11050283.
Habashy, Engy, and Tobias S. Köhler. “Botox for Erectile Dysfunction.” The Journal of Sexual Medicine 19, no. 7 (2022): 1061–63. https://doi.org/10.1016/j.jsxm.2022.03.216.
Porter, Dr Mark. Botox: The New Viagra? It’s One Way to Treat Erectile Dysfunction. Sec. Times2. n.d. Accessed November 8, 2022. https://www.thetimes.co.uk/article/botox-could-help-men-beat-erectile-dysfunction-here-s-what-to-know-8x2vvt9c7.
Research – Priapus ToxinTM. n.d. Accessed December 17, 2023. https://priapustoxin.com/research/.
Saadawi, Badr, Abdulmajeed Alghamdi, Alaa Abdulrahman Ismail, et al. “Efficacy of Botulinum Toxin Injections for Erectile Dysfunction and Premature Ejaculation: A Meta-Analysis of Randomized Controlled Trials.” Current Drug Research Reviews 18 (March 2026). https://doi.org/10.2174/0125899775434881260214052930.
Shehri, Zaed Ghassan, Issam Alkhouri, Mohammad Y. Hajeer, Ibrahim Haddad, and Mohamad Husam Abu Hawa. “Evaluation of the Efficacy of Low-Dose Botulinum Toxin Injection Into the Masseter Muscle for the Treatment of Nocturnal Bruxism: A Randomized Controlled Clinical Trial.” Cureus, ahead of print, December 4, 2022. https://doi.org/10.7759/cureus.32180.
Silva, João, Rui Pinto, Tiago Carvalho, et al. “Intraprostatic Botulinum Toxin Type A Administration: Evaluation of the Effects on Sexual Function.” BJU International 107, no. 12 (2011): 1950–54. https://doi.org/10.1111/j.1464-410X.2010.09841.x.

Vampire Facelift® Research

1. Hom DB, Linzie BM, Huang TC. The healing effects of autologous platelet gel onacute human skin wounds. Arch Facial Plast Surg. 2007;9(3):174-183.

2. Sclafani AP, Romo TR III, Ukrainsky G, et al. Modulation of wound response and
soft tissue ingrowth in synthetic and allogeneic implants with platelet concentrate. Arch Facial Plast Surg. 2005;7(3):163-169.


3. O’Connell SM, Impeduglia T, Hessler K, Wang XJ, Carroll RJ, Dardik H. Autologous
platelet-rich fibrin matrix as cell therapy in the healing of chronic lower extremity ulcers. Wound Repair Regen. 2008;16(6):749-756.

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4. Cervelli, Valerio MD; Lucarini, Lucilla MD.Use of Platelet-Rich Plasma and Hyaluronic Acid in the Loss of Substance with Bone Exposure. Advances in Skin & Wound Care: April 2011 – Volume 24 – Issue 4 – pp 176-181 [This one shows using the same techniques used in the Vampire Facelift (R) procedure to grow new skin WHERE THERE IS NO SKIN]

5. Redaelli, Alessio. Face and neck revitalization with Platelet-rich plasma (PRP): clinical
outcome in a series of 23 consecutively treated patients. Journal of Drugs in Dermatology – May 1, 2010

6. Azzena B, Mazzoleni F, Abatangelo G, Zavan B, Vindigni V. Autologous platelet-rich [Using Regen prepared platelet-derived growth factors (a single-spin centrifuge) to rejuvenate the face & neck]
Plasma as an adipocyte in vivo delivery system: case report. Aesthetic Plast Surg. 2008;32(1):155-161.

7. Cervelli V, Gentile P, Grimaldi M. Regenerative surgery: use of fat grafting combined
with platelet-rich plasma for chronic lower-extremity ulcers. Aesthetic Plast Surg. 2009;33(3):340-345.

8. Cervelli V, Palla L, Pascali M, De Angelis B, Curcio BC, Gentile P. Autologous
platelet-rich plasma mixed with purified fat graft in aesthetic plastic surgery. Aesthetic Plast Surg. 2009;33(5):716-721.

9. Cervelli V, Gentile P. Use of cell fat mixed with platelet gel in progressive hemifacial atrophy. Aesthetic Plast Surg. 2009;33(1):22-27.

10. Cervelli V, Gentile P, Scioli MG, et al. Application of platelet-rich plasma in plastic surgery: clinical and in vitro evaluation. Tissue Eng Part C Methods. 2009; 15:1-9.

11. Sclafani AP. Platelet-rich fibrin matrix for improvement of deep nasolabial folds. J Cosmet Dermatol. 2010;9(1):66-71.

12. Sclafani AP. Applications of platelet-rich fibrin matrix in facial plastic surgery. Facial Plast Surg. 2009;25(4):270-276.

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13. Sclafani AP. Safety, efficacy, and utility of platelet-rich fibrin matrix in facial plastic surgery [published online February 21, 2011]. Arch Facial Plast Surg. 2011;13(4):247-251.

14. Kakudo N, Minakata T, Mitsui T, Kushida S, Notodihardjo FZ, Kusumoto K. Proliferation-promoting effect of platelet-rich plasma on human adipose-derived stem cells and human dermal fibroblasts. Plast Reconstr Surg. 2008; 122(5):1352-1360.

15. Oh DS, Cheon YW, Jeon YR, Lew DH. Activated platelet-rich plasma improves fat graft survival in nude mice: a pilot study. Dermatol Surg. 2011;37(5):619-625.

16. Danielsen P, Jørgensen B, Karlsmark T, Jorgensen LN, Agren MS. Effect of topical autologous platelet-rich fibrin versus no intervention on epithelialization of donor sites and meshed split-thickness skin autografts: a randomized clinical trial. Plast Reconstr Surg. 2008;122(5):1431-1440.

17. Anitua E, Sa´nchez M, Zalduendo MM, et al. Fibroblastic response to treatment with different preparations rich in growth factors. Cell Prolif. 2009;42(2):162-170.

18. Carroll RJ, Arnoczky SP, Graham S, O’Connell SM. Characterization of Autologous Growth Factors in Cascade Platelet-Rich Fibrin Matrix (PRFM). Edison, NJ:Musculoskeletal Transplant Foundation; 2005. Publication No. 128-XM 307C5.

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19. Anthony P. Sclafani, MD; Steven A. McCormick, MD. Induction of Dermal Collagenesis, Angiogenesis, and Adipogenesis in Human Skin by Injection of Platelet-Rich Fibrin Matrix. Arch Facial Plast Surg. Published online October 17, 2011. [Biopsy-proven new blood vessel growth and new collagen using platelet-derived growth factors (using a single-spin centrifuge)]

Find the nearest Provider of the Vampire Facelift® Procedure

Sponsored by the Cellular Medicine Association<–

Vampire Facial® Research

Original article: Platelet-rich plasma with microneedling in androgenetic alopecia along with dermoscopic pre- and post-treatment evaluation. [“Hair growth started after the first session.”] click to read<–

Skin microneedling plus platelet-rich plasma versus skin microneedling alone in the treatment of atrophic post acne scars: a split face comparative study. [“There was a significant improvement in the degree of scar severity before and after treatment”] click to read<–

Review of applications of microneedling in dermatology [“Overall, the procedure has few adverse sequelae compared to other therapies, is highly efficacious, and is a viable resurfacing option for skin of color.”] click to read<–

Microneedling: A Review and Practical Guide [“Microneedling is a safe, minimally invasive, and effective esthetic treatment for several different dermatologic conditions including acne and other scars, rhytides, and striae. Given its expedient post-treatment recovery, limited side effect profile, and significant clinical results, microneedling is a valuable alternative to more invasive procedures such as laser skin resurfacing and deep chemical peeling.”] click to read<–

Find Provider of the Vampire Facial® Procedure<–

A Comparative Study of Microneedling with Platelet-rich Plasma Plus Topical Minoxidil (5%) and Topical Minoxidil (5%) Alone in Androgenetic Alopecia. [“Microneedling with PRP is safe, effective, and a promising tool for the management of androgenic alopecia.”] click to read<–

Therapeutic effect of microneedling and autologous platelet-rich plasma in the treatment of atrophic scars: A randomized study. [“…combination between skin needling and platelet-rich plasma is more effective, safe with less number of sessions in all types of atrophic scars.”] Click to read<–


Young woman demonstrates the science explaining the Vampire Facelift® & Breast Lift® procedures. from Charles Runels, MD on Vimeo.

Microneedling therapy with and without platelet-rich plasma. [“PRP appears to augment the cosmetic outcomes of microneedling without increasing the risk for adverse events.”] click to read<–

*GH Sasaki, Micro-Needling Depth Penetration, Presence of Pigment Particles, and Fluoresecein-Stained Platelets: Clinical Usage for Aesthetic Concerns; Anetht Surg J. 2016 Aug 16 [“Demonstrated statistically significant improvements (P ≤ .05) in wrinkle effacement, skin laxity, scar softening, and hair growth”] (click to read)<-

*Ensuring Consistent Results When Microneedling Perioral Rhytides.

*MICRONEEDLING – A FORM OF COLLAGEN INDUCTION THERAPY – OUR FIRST EXPERIENCES. [shows helpful for treating burn scars]. click to read<–

*Microneedling in Dermatology: A Review [it works]

*Platelet-rich plasma versus CROSS technique with 100% trichloroacetic acid versus combined skin needling and platelet rich plasma in the treatment of atrophic acne scars: a comparative study. 2017 Jan;37(1):71-83. Epub 2016 Aug 16. [“Showed a promising efficacy and safety in the treatment of atrophic acne scars.”]

More Research<–

Skin needling as a treatment for acne scarring: An up-to-date review of the literature. 2015 Apr 10;1(2):77-81. doi:10.1016/j.ijwd.2015.03.004. eCollection 2015 Jun. [“Evidence to suggest that skin needling is beneficial and safe for the treatment of acne scarring.”] click to read<–

Combined autologous platelet-rich plasma with microneedling verses microneedling with distilled water in the treatment of atrophic acne scars: a concurrent split-face study. click to read<–

We Could Use Your Help Filling the Following IRB-Approved Studies

• Double-blind placebo-controlled study of the O-Shot procedure for orgasmic dysfunction.+ We can use some help filling this study.
• Double-blind placebo-controlled study of the O-Shot procedure for lichen sclerosus

More about the Cellular Medicine Association<–

1-888-920-5311

 

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Disclaimer

*This website is intended solely as professional education for licensed healthcare providers. It is not medical advice, not patient-directed advertising, and not an offer to treat any individual. Nothing here should be used by a member of the public to diagnose or treat any condition; patients should consult a qualified, licensed physician about their own care. The procedures and platelet-rich plasma (PRP) applications discussed are investigational and/or off-label. They have not been evaluated or approved by the U.S. Food and Drug *Administration (FDA) for the uses described, and the FDA has not approved PRP or these procedures to diagnose, treat, cure, or prevent any disease: PRP is a blood product that belongs to the patient, not a drug, and is not regulated by the FDA; also the FDA regulates drugs and devices, not procedures. References to the O-Shot®, P-Shot® (Priapus Shot®), Clitoxin®, Vampire Facial®, Vampire Facelift®, and other trademarked procedures describe training methods and clinical approaches; they do not imply FDA clearance or guaranteed outcomes.

*The content reflects a review of the published literature and the clinical opinions and experience of the author. Comparisons to FDA-approved drugs or surgical options (for example, references to a procedure as “first-line”) represent the author’s interpretation of the cited studies and individual clinical judgment — not established medical consensus or proof of superiority, safety, or efficacy. Individual results vary, and no specific outcome is promised or guaranteed. Statements regarding the absence of reported adverse events reflect the limits of the available evidence base and should not be read as proof of zero risk.

*Any clinical decision remains the sole responsibility of the treating licensed provider, who must exercise independent professional judgment, obtain appropriate informed consent, and comply with all applicable laws, regulations, and standards of care in their jurisdiction. The author and the Cellular Medicine Association assume no liability for actions taken based on this information.