JCPM2019.7.10VampireFacialResearch.TearTroughs.BagsUnderEyes.OShotPearls.DyspareuniaPostRadiation

Topics Discussed Include the Following…

*Vampire Facial® techniques reviewed in Facial Plastic Surgery Clinics of North America, August 2019
*When to activate PRP with Calcium (chloride or gluconate)
*Tear Troughs & Bags Under the Eyes
*PRP with or without Amnion in the Neck
*Dr. ‘Tangchitnob’s Pearls About Doing the Vampire Facelift® Procedure
*Selecting the Best Patients for the O-Shot® Procedure
*Dr. Tangchitnob’s Pearls for Doing the O-Shot® Procedure
*2 Guiding Principles That Bring More Patients and Provide Better Care
*Dyspareunia after radiation–Can/How improved with the O-Shot® Procedure
*Pelvic Floor Spasm
*A Nine Minute Cram Course on Marketiing Your Mecial Practice, Timeless Intimacy™, and Virtual Assistants from an Engineer/Physician’s Perspective

Video/Recording of CMA Journal Club, Pearl Exchange, & Marketing Tips

Transcript

Vampire Facial® Procedure in Facial Plastic Surgery Clinics of North America

Dr. Runels: This should be a really wonderful meeting tonight. We’ve got new research, and we have the amazing Dr. Edward Tangchitnob who is out in California, award winning for his practice, and brilliant gynecologist, and surgeon, and teacher of our procedure. This should be an interesting call. We have some new research I want to just bring up very quickly. First, let me bring Dr. Edward onto the call. Let’s see, hold on just a second. I’m going to unmute you here. There’s a couple of research things that are out that I think are really nice. Hold on just a second. Let’s see.

Edward, I’m not sure what’s going on with your mic. I don’t know if you will need to call. It looks like your audio might be turned off or something. Let me go ahead and bring up the research and as soon as I see your mic light up I’ll unmute you. Let’s see if there is something here. Anyway, so I’ll be watching for that. I can see Dr. Tangchitnob on the call but I don’t … Okay, there it is. There’s your microphone. Here we go. Beautiful. There you are. Can you hear me.

Dr. Edward T: I can.

Dr. Edward Tangchitnob, MD, ACOG

Dr. Runels: Beautiful. Look at this. Just a review article but it came out in here it is, in Facial Plastic Surgery Clinics of North America, August 2019. I don’t think you could see a better endorsement. I mean, there’s the abstract. “Platelet rich plasma has gained popularity in facial plastic surgery because of it’s healing and growth factors.” But then this is the part I love, “One of the most popular uses facial skin rejuvenation in the form of injections and topical application during microneedling …” That would be in for a facelift and facial, “… and the promising nature makes using it for injection or conjunction with microneedling a good addition.” Beautiful. That sounds like a pretty strong endorsement in that journal, or in that periodical. This is the article I wanted you, and I put a link to that. Actually, I didn’t yet, but let me put a link to that into the chat box, you guys.

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Using Scientific Research to Educate and Market To Your Patients

That’s a good one to take … If you just take this link ( https://www.sciencedirect.com/science/article/abs/pii/S1064740619300331?via%3Dihub) and you put it in an email or a Facebook post and you shoot that out to your people and say, “Hey, here’s some research that came out this month.” Here’s a little trick about … It’s just commonsense, actually, for how to talk with your patients, is make, when you have this this counts as news. We’ve all heard on CNN or whatever news channel you listen to where they talk about something, they usually report it out of the New England Journal, because the guy on the street knows that’s a reputable journal. But, often it’s the news reporting on the news. This is news, and you could call up your news channel and say, “This is what I do.” You could also just post this to your social media, or an email to your people and say, “Hey, look what came out this month, more nod of approval from the the powers that be, that this is something that’s useful, and this is what I do.”

I want to shoot over … Any comments about how you’ve been doing that, Edward? I know you’ve had some success with your marketing. Talk to us about how you’ve done things like this.

Dr. Edward T: I think that there’s a lot of information out there at the fingertips of all the patients. They’re getting bombarded constantly from their Twitter feeds, their Instagrams, their Facebook. I think everyone, and anyone, really can be the so-called expert on a particular topic. When I’m emailing my patients, and I make a habit of it every two weeks using Ontraport email client,

I think that we have a very captive audience, because the patients already know and trust us, and the open or the click rate is a lot higher, especially when it comes from us. I’ve also played around a few times with the subject line. I’ve done split testing to kind of see what kind of topics and what kind of tone of the subject, or the copy, can resonate with my patients. I’ve been actually surprised a few times in the split testing. That was something I kind of picked up along the way.

Just to kind of give you an idea, a year ago I didn’t even know what Ontraport was, or an email client was, let alone what split AB testing was. But, as I’ve come along on this journey I’m finding that my ability to communicate to my patients in sophisticated ways is being appreciated. The way I’m measuring it is that I’m able to see that the number of conversations, booked appointments, and paid procedures is going up. Just as you’ve said before, the more we seem to email and communicate the more the patients are aware of the procedures that we’re performing, and the more that they’re aware that their procedures are available from the physician, or the practice they’ve trusted all these years, the conversion rate, I think, is a lot higher.

Dr. Runels: Yeah, let me expand on a couple of important points you made that I failed to make. One is that people are bombarded, but for your patients, you being whomever is on this call, and for my patients, and Edward for his patients, they are more interested in … Because they’re bombarded it’s confusing to them. As you just said, Edward, they want us to curate that and point out to them what’s important and occasionally, I think the ratio should be mostly what’s good, but occasionally point out to them something that may be popular that you don’t think is as useful. As a general rule that’s more of a waste of our energy to talk about what’s not good, but being the curator I think we tend to think, “Why do they care about what we think since they’ve got CNN, and the Mayo Clinic Newsletter, and the Cleveland Clinic Newsletter?” I actually talked to a man today that helped the Cleveland Clinic start their newsletter. They’re doing exactly what you just said, for people who wind up going to the Cleveland Clinic they want to know what the Cleveland Clinic thinks.

My patients, and Edward’s patients, and everybody else on this call, they’re more interested in what we think than what the Cleveland Clinic thinks. So, sending that out every couple of weeks, and making it something that reports, this is your perfect … This is what you wait for, and you don’t have to wait long on their procedures because we’re in the news so much. But, you shoot this out and now you’re not spamming people, you’re reporting on the news just like CNN does.

The second thing you said is that just the general idea that when I said expand on this, the idea that email still is the powerful way. Even when you post to Facebook it doesn’t get shown to all of your friends, and they’re so bombarded, and it’s limiting the conversation. Sometimes it gets banned if it’s some picture about, or something about, sex. The old email to your patients is still, in my opinion, the most powerful way to get things done.

When to activate PRP with Calcium (chloride or gluconate)

Okay, let me pull up this other … You know, I think I’ll hold off on the other research. There’s something here about … I just wanted, since you’re an expert surgeon I wanted to talk some about how PRP’s been used in surgery. Let’s skip over that and maybe do a question. This one comes up occasionally about calcium chloride. “I used to use calcium chloride. I started with Selphyl,” so the short answer to this is if you Selphyl it comes with a kit. With the others you can either order it as, it’s the same calcium chloride that’s in your crash cart or, and here’s … I’m on the O-Shot website. The reason I’m not pointing it out to the Vampire Facelift website is I quit using calcium in the face. It makes it hurt more. If I have a Selphyl kit I just leave it out.

But, you can use the same calcium that comes in a crash cart and mix it in with … So, I took it off the Facelift site, but you can mix it with the PRP. This is a video showing you how to do it, so you can take that ampule, mix it in to just a 10 cc syringe and then use that syringe as a dispensing vial into an empty syringe and then put your PRP into that, obviously not cross-contaminating that. You can make this into a multi-dose vial.

There’s a source of it at mrcrashcart.com. It’s where you get your calcium chloride. That’s 10% calcium chloride. Also, you can get it at McGuff, which is the same place where we get our syringes, and it’s on this supply list that sits up here. There’s your supplies in the PDF file right there, and where I get some of it. There’s the phone number, there’s the email for McGuff, and that’s basically if you order everything on that you can do pretty much all of our procedures if you have a PRP kit.

What’s your … Edward, I know I really stress using calcium chloride for the O-Shot® and the P-Shot®, and if you’re trying to grow nerves. Say you lost the sensation in the breast. I’ve quit stressing it. I don’t see people talking about it much with hair anymore, or with the face. Is that still what you’re doing, or have you altered that in any way? What are you doing when it comes to calcium chloride, or calcium?

Dr. Edward T: No. I still follow the teaching that I was given originally, which is exactly what you had mentioned. I’m finding, particularly, with the Vampire Facelift®, for example, the ability to kind of spread over the cheeks and in the nasolabial folds, as well as run down very finely in the tear trough, I don’t use calcium chloride to activate. It would be a little bit to viscous, in my opinion.

Tear Troughs & Bags Under the Eyes

Dr. Runels: And there is that idea that, which you just mentioned, is that with the O-Shot® you want it to gel quickly and stay in a pretty small area, relatively speaking, where with the scalp and the face you want a more diffuse spread. This right here, I think, is a really important point. Dr. Hamilton has someone who has some bags under the eyes after injecting. I recommend, and the question is, “What do you do?” Absolutely I’ve treated a lot of people who came in with … The tear troughs, not so much in the lower lid, but in the tear trough area if it is convex I can almost guarantee you there’s filler in there. I’m seeing people say, “No, it’s not filler,” and then I put a hyaluronic base in it, just a little dot, and it goes away. When I say a dot I mean one unit on a 30-unit insulin syringe is what I do with a 31 gauge insulin syringe and just put 0.01 mL in there, or one unit on that insulin syringe, and it goes away.

But, if you don’t have a lot of experience with using fillers I just wouldn’t use. I would use PRP as a stand-alone in the tear troughs, or do a mixture of one part JUVÉDERM® and nine parts PRP, so 0.1 of JUVÉDERM® and 0.9 of PRP in a 1 cc syringe, swished around, and use that and this is less likely to happen. But, it is fixable. I know you sent me some amazing pictures, Edward. Do you have any of those handy that you could show us? And, you can talk about what you’re doing, because I know you’ve developed some pearls around the face. Do you have any of those handy that I could just hand you the screen and you could talk to us about what you’re doing?

Dr. Edward T: Sure. Give me one second here.

PRP with or without Amnion in the Neck

Dr. Runels: Yeah, that’s cool. I’ll talk about this next question while you’re pulling that up. “Any protocol for injecting PRP with or without Amnion into the neck?” I think we covered this, actually, on the last call, but just to review. I think if you’re working with the neck I’d do three things. Again, if it’s a turkey neck they need a surgeon. I send lots of people for blephs, and for neck lifts, and facelifts. If it’s just necklace lines, or if there’s some platysma looseness that I can fix with Botox® then I go for it, and people love it. I charge for the PRP part of it 600 bucks. What I’ll do is … I treat it like a scar, basically. So, in the necklace lines I’ll put 27 gauge needle into the necklace line and inject intradermally and subdermally with PRP, and then microneedle PRP on top of that.

Then, if you’re going to mix Amnion with it, I just use one of those half cc Vampire Amnion. You know we have our own brand now that’s about one-fifth the price of what most people charge and it’s good stuff. You put a 0.5 cc of that, or a half a cc of that to 5 cc of PRP and mix it up and then inject it. Then, Botox® 2 units along the line about every inch or so apart, and then put them on a good cream, put them on our Altar® Cream. If you want to go all out, put them on Retin-A 0.1% cream at night and our Altar® Cream in the morning and they get amazing results. You found some pictures for us, Edward?

Dr. Edward T: I did.

Dr. Runels: Okay.

Dr. Edward T: Let me see if they-

Dr. Runels: Yeah, I’m going to hand you the … By the way, you guys, Edward teaches a great class where … Actually, let me just give you the screen. I want you to show us your pictures and then we can talk about your class. Let’s see.

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Dr. Edward T: I’ve got a great story about this first case, if I have control of the screen here.

Dr. Runels: All right. It should be offering it to you right now.

Dr. Edward T: Do you see what I see here?

Dr. ‘Tangchitnob’s Pearls About Doing the Vampire Facelift® Procedure

Dr. Runels: Yep? I got you. She’s 55-60 year old woman treated with Vampire Facelift®.

Dr. Edward T: Originally, to take us back, this patient found me. She had actually moved, her and her husband from Tennessee and found me for an O-Shot®.

Dr. Runels: Beautiful.

Dr. Edward T: We ended up doing an O-Shot® on her and there’s so much crossover with the PRP procedures that she asked about the Vampire Facelift®. Naturally, we ended up doing a facelift on her. Now, this was one of my great kind of before and afters, because she had such a great result both from kind of the textural component as well as the shape. Staying with the classic form here I ended up … I just used one syringe. I used [inaudible 00:16:07]. I did some [inaudible 00:16:08] around her PRP, and that’s the result she got. My pearl is with this particular case I remember … I think that I was able to achieve the lift I did really by pulling, doing a pulling technique. When I first started doing these injections I would go right on the periosteum, right where the zygomatic arch is.

I still do that, but now I pull up very aggressively, and I draw Dr. Hinderer’s lines, which you can see here kind of mid [inaudible 00:16:41] down to the lateral aspect of the nose, and the lateral canthus down to the mouth. See where my finger is, this pointing arrow what I do is I lift and pull up really, really high on the skin and you can actually see where that line used to be, the one I drew when you kind of pull the skin up taut. I inject where the line used to be. What I mean by that is that for patients who are over the age of 40 who have a little bit more heaviness and need more lift I’m really kind of pulling up and I’m using the filler as a tack.

Dr. Runels: Interesting.

Dr. Edward T: I think before I was, basically, just filling down to the level of the bone hoping that it would just raise the skin. But with this technique when I’m drawing Dr. Hinderer’s lines I’m pulling the skin as high as I can. I inject with my right hand, so I pull with my left hand, and then I kind of see where that line used to be and I inject there. Obviously, when you pull the skin up with your left hand here, the line you drew goes up. So, the line you can imagine that used to be there is where I inject. That’s kind of the after that I get here. There’s a lot more kind of superolateral projection doing this pull and lift technique. I started developing this because as I’m getting into the more longer-lasting fillers such as Voluma®, that’s actually how Allergan teaches it. Now, I’m combining this lift and pull technique with the Vampire Facelift®, which was my introduction to facial aesthetics when I first learned this from you, Charles.

Dr. Runels: Beautiful. So, can we go through that again? So, you draw the lines and then you pull-

Dr. Edward T: What I do is … Right. So, I draw the lines and then I pull up on the lateral aspect of the cheek just as high as I can with my non-injection hand. Where the line used to be, now that it’s been moved up, that’s where I inject.

Dr. Runels: While you’re holding it up?

Dr. Edward T: While I’m holding it up.

Dr. Runels: Okay, beautiful. You’re directing all along the lateral zygomatic arch there. Is that what you’re … Okay.

Dr. Edward T: I’m doing the 0.15 and the 0.5 is classically descried by the Vampire Facelift®. I think I’m getting more bang for my buck when I’m thinking about using it as a tack rather than as a fill, and then I put the PRP over it and it seems to work really well with that lateral superolateral projection.

Dr. Runels: That’s some beautiful photographs. What are you doing around the tear trough area? I hear lots of different techniques for the tear trough. I like that technique where you’ve taken the best of Allergan’s teachings and then one upped it with your Vampire ideas. Talk to me about … By the way, if I were defining the Vampire Facelift® it would be like this. Take a syringe of filler, do your best work with it, polish it off and think of that as reshaping the mattress, keeping in mind the ideas that you just mentioned about shaping the, restoring the youthful shape of around the eye and the mid cheek area especially, because that’s where research shows that we first get an idea about our perception of how old someone is. So, that’s where you start and then you think about the other things that are described on the website based on your understanding of the face and your understanding of your best technique.

I never expect everybody to do it exactly the same way. We all have different eyes on different days and with different people. As long as those techniques are used then they’re going to have the best result possible. It’s just what’s going to happen. So, that’s the Vampire Facelift®. Around the tear trough, and we all have a different way of seeing it, but we’re all following that basic principle, using HA, make your best useful shape, polish it off with PRP, and then if you need more HA that’s fine go for it, but let that be additional cost to the patient since it’s additional cost to us, and that way we’re all going about the same guidelines as far as our pricing, as well. The tear trough, though, is where I see the most variability, so talk to us about what you’re doing since that was one of the questions tonight.

Dr. Edward T: Absolutely. I get very, very medial all the way up almost to the nose, and then I inject and I’d watch the PRP fall backwards. I don’t activate, by the way. One of the risks that I … Actually, one of the side effects of this particular technique is I almost always get a little bit of bruising, and so they get kind of that darkened shadowing after I do a Vampire Facelift®. It goes away and I assure them of that, but I’ve been getting really great outcomes with it. I also get better outcomes I’m finding when they come back four to six weeks later, and I only inject their tear trough with PRP. I think sometimes the first PRP injection might not be enough, particularly if they are almost on that borderline of needing a lower bleph. I also finish it with Lytera®, which is a skin cream made by SkinMedica® that helps with pigment. I learned that one from an oculoplastic colleague of mine who gave me that pro tip.

Dr. Runels: Beautiful. Thanks for the pearl. That’s why we do this at night. Let me ask you for a little bit more clarification, though. You started that explanation by talking about doing something more medially. Can you talk more about what you meant by that.

Dr. Edward T: Absolutely. If I may use my … If you can still see my screen here, I’ll use this picture. My needle originates or goes in here and goes all the way to the most medial aspect of the eye near the nose here. I’m going to zoom in here slightly. To me I see this triangular shape here that I want to fill, because when I go through this crepey, or there’s almost always kind of crepeness here of the skin. The bag, or the space here, is so thin here it fills so well with that unactivated PRP that it filled all the way up to here and comes back. I don’t know if that was by design or not. I suppose to try to get rid of your tears as you kind of tear, but it’s natures way of very efficiently kind of whisking away excess fluid there. I’m just kind of leveraging that shape.

Dr. Runels: Interesting. Would you say the name of that cream again that you’re using, and you’re using it for the crepe papering in the lower eye area? Is that right?

Dr. Edward T: Correct. It’s actually Lytera® 2.0. It works great because it works well for the color. In those patients who have an ethnic predisposition to bags under their eyes this alone works fantastic. That’s where I got the idea to begin pairing this with that part of the Vampire Facelift® that involves injection of PRP under the bags of the eyes.

Dr. Runels: Just so you guys know. You may have picked up already, Edward has a strong background in mathematics as an engineer and then is a world-class and award-winning robotic surgeon and gynecologist there in Southern California, and does a really beautiful job of teaching combination therapies, teaches BioTE®, so he teaches hormones and he teaches lots of ways of thinking about how these procedures can be combined with energy sources and surgical techniques. With that introduction, can you pull us up some pictures and talk to us some about your ideas about the O-Shot®, starting with maybe, if it’s handy, maybe that picture you have of the urethra, which I think is amazing. But, talk to us more … I want to get back to marketing, because you’ve been really successful with the marketing.

Selecting the Best Patients for the O-Shot® Procedure

First, talk to us some about your ideas about patient selection. I never want to get away from the idea that the better we are about patient selection, that’s the first step to having great results. All of us want to have wonderful results and be paid appropriately for doing, basically, miracles with our patients. Can you first start with explaining this picture and then some patient selection pearls?

Dr. Edward T: Absolutely. To kind of go a step back, as an engineer I think that it’s very important to define and measure all the activities we do. As a physician I try to look for those tools in our clinical toolbox to measure these outcomes. When I had done my fellowship in robotic and urogynecologic surgery at Scripps Clinic in San Diego, one of the kind of key aspects of my training, even before I started doing pelvic surgery, was urodynamics. Urodynamics to me is the gold standard for actually assessing the different kinds of urinary incontinence. Does the patient come with a pure stress urinary incontinence? Do they come with a overactive bladder picture? Or, is it more commonly the most common kind, which is mixed, which is actually the most difficult to treat. So, when I do my assessment of the patients for their candidacy I think it’s ideal when you do the full work up, although it doesn’t happen every single time, to have some kind of urodynamic evaluation.

The area that I look at, and I’m most interested in … Actually, I’m going to scroll down here, is the intrinsic sphincter deficiency assessment, or the urethral closing pressure, because I really want to know at the urethra what the degree of damage or the degree of strength that resides. To me at one end of the spectrum you have a very healthy urethra that upon closure can actually withstand the increased pressures that are created when the patient laughs, coughs, or is a little bit heavier. That’s a young patient, maybe they’ve not had kids before. They cough real hard they’re not going to leak, because the urethral pressures and that intrinsic urethral strength is quite strong.

On the very other end of the spectrum, you have a patient who has intrinsic sphincter deficiency in which the urethra takes on more of a complete pipe shape and function. In the case of the patient with intrinsic sphincter deficiency, when you perform urodynamics on them you will see that their urethral closing pressures are way less than 50 mmHg. They’re actually quite low. In my opinion, the patient who is healthy, who can be continent when they cough really hard, versus the patient who has intrinsic sphincter deficiency, somewhere lies in between the ideal patient for doing an O-Shot® for urinary incontinence.

I’m thinking, in my mind, Charles, that the patient who doesn’t have a lot of tone to begin with … You could probably do four or five O-Shots® on them, several lasers, even putting a sling on them, and it may not work. Why? Well, I think by nature that urethra it’s too damaged or it’s not functional. Many of our procedures that are noninvasive, such as doing an O-Shot®, or doing two, or even giving them testosterone in the form of a pellet that causes hypertrophy of the muscles that surround the urethra, may not work. In fact, when you kind of do the literature search, one of the gold standards for performing a treatment on someone with intrinsic sphincter deficiency is to do a TVT, or perform a TVT, a transvaginal tape, in which it’s a lot of back support against that urethra does not work that well.

If you look at … I’m a big fan of the mini-sling, the Solyx. For those of you who are on the call right now, mini-sling is a very small sling that’s usually called the minimally-invasive sling, because it’s so small and doesn’t pierce through any of the spaces, may or may not give as much of that backstop support for someone with ISD.

What does that mean for all of us performing and looking for the ideal O-Shot® patient. Well, I would actually really use the history to try to guide us. How long has the incontinence been going on? Are there things that you can do, or things that you’ve tried? Some patients have been very good about doing Kegel’s muscles and Kegel training. They get some improvement upon doing these Kegel muscles. They just can’t get to it every day. I mean, we have such busy days. To do Kegel muscles with intent it’s just so difficult. That patient is a good O-Shot® patient, because they can demonstrate that with some exercising they could bring back that tone.

Someone who has had … I actually saw a patient today. She had had two C-sections. I’m about to do an O-Shot® on her next week. I think she’s a good candidate. We just did her urodynamics. We’ve proven that her urethral closing pressures are well above 50 mmHg. It makes sense in her history that probably with time, age, and the decrease of hormones that that tone or incontinence is changed. I think she’s going to be a fantastic candidate for an O-Shot®. These very soft findings in the history, not all of us have urodynamics ready to do in the office, I think really guide our ability to find that O-Shot® patient. Sometimes it might take another O-Shot®, for example.

Dr. Runels: Can I ask you two quick questions? First, for the person who doesn’t have the ability to make those measurements could you elaborate more on what clinical history or physical findings they might use that you’re correlating with those measurements? Second, do you have the beginnings of a data bank measurements before and after an O-Shot® that we could publish somewhere?

Dr. Edward T: I’m beginning to collect that score, because very early on, which is why I’m referencing this picture, I wanted to find a way to measure, if not visually, at least quantify the difference in the closing pressures after doing an O-Shot®. Now, this particular publication, or this article submission, was a case report of a 48-year-old gravida 5 para 2 … Actually, wow, last year. Almost by design a year ago that I had published, and this was after we did an O-Shot® in the operating room for a patient we did robotic surgery on. You can see here before the O-Shot® I put the cystoscope in. This was a 30-degree Stryker cystoscope, and you can see what the urethra looks like before the O-Shot®, and this is immediately after. I can imagine with time that the O-Shot®, the effects of the O-Shot® platelet rich plasma probably would just improve the tone of the urethra.

I actually don’t have, and I wish I did, pictures in a series of what happens at 30, 60, and 90 days, because I don’t know how I would consent a patient to do cystoscopy just to see how the O-Shot® is doing. More rather, bringing the patient in and just kind of asking what their incontinence level is.

The second part I think you were asking is, looking at a questionnaire, which is what we did, I’d be happy to share with the group, too. There’s a great one developed by LABORIE who makes my urodynamics equipment. It’s a checklist of about ten questions that, basically, look to see, Do you feel like you have to pee as soon as you put the key in the door? We call latch-key urinary incontinence, which really speaks more towards overactive bladder. Or, Do you leak when you cough? How many pads are you using a day? You could almost get a gestalt on whether they have stress urinary incontinence or overactive bladder, for which the two treatments are different. I am seeing almost in colloquial, or kind of informally, that the patients with overactive bladder are needing to use less Detrol, something about their O-Shot® and rejuvenating some of the vaginal mucosa immediately underneath the bladder helps with overactive bladder.

Dr. Runels: Anecdotally we’ve had some people with very severe cases that have made remarkable changes, so hopefully you can get us some objective numbers that we can publish somewhere. Can you give us your pearls about actually doing the procedure, and thank you for showing those pictures and, yes, we would like to see that survey you’re using for measurements.

Dr. Edward T: I’ll get that to you and maybe you could distribute it out to-

Dr. Runels: I’ll just post it on the web … Is it copyrighted? Is it something we can post?

Dr. Edward T: It’s pretty general.

Dr. Runels: Okay, I’ll post it to the membership site for people to download. Would you talk to us about your pearls about how you think, what you’re thinking, when you actually do an O-Shot®?

Dr. Tangchitnob’s Pearls for Doing the O-Shot® Procedure

Dr. Edward T: Absolutely. So, when I talk about … I’ve experienced in two realms and I’m very fortunate because, I think I’ve told you this before, my hospital system has been extremely supportive with regenerative medical techniques that I’m doing in the OR. My story in terms of the OR, versus doing it in the office, which I’ll talk about in a second, really stem from a product made by Stryker. Stryker made a product called Vetigel® and Vetigel® is a combination of autologous PRP in which the scrub tech or the nurse that would have to draw the patient’s blood and then mix it human thrombin and that’s what our GYN oncologists and I were using to put on the vaginal cuff before I even took your class, Charles. This is …

Dr. Runels: Interesting.

Dr. Edward T: … before I took your class. We were finding that the rate of vaginal cuff dehiscence and post-robotic hysterectomy spotting went to nil. One of the most frequent calls that we get as a gyne robotic, or any kind of gyne surgeon, is post-hysterectomy spotting, because the cuff has little pores through it. We were just plugging the Stryker Vetigel®, which is really just PRP plus thrombin, over the cuff and the patients had less pain. They were not spotting. We had less calls. We were happy.

Gyn Surgery with PRP as Adjunct<--(click)

Then about three months later it made me so sad because Stryker pulled the product off the shelf. In my very engineer mind I said, “You know what, this is just too good of a product to not have on the shelf,” so I started looking at other companies. We use Regen. We were able to replace a pre-existing product in our hospital OR with a similar product. I think I found a very pleasant loophole, right, because I had to have something to replace it, so we found something to replace it that ended up being a lot cheaper.

Dr. Runels: You’re referring to Regen when you say there’s something to replace it? Regen Therapy?

Dr. Edward T: Yeah.

Dr. Runels: Okay. I’m going to put a link … I don’t want to stop your flow and I’m not changing the subject. I’m just going to put a link into the chat box, guys, with a few … to just a PubMed page that shows a few, four papers, about using PRP in surgical situations, one with mesh, one with rectal-vaginal fistula, along those similar lines. So, when you’re using this as part of a hysterectomy are you making a gel with your Regin kit, or how are you processing it to make it do the same thing that the previous Vetigel® was doing?

Dr. Edward T: When I do it with my hysterectomy, I do make it with a gel, and I [inaudible 00:36:47] calcium chloride, and I add about 0.1 of thrombin, that is autologous thrombin.

Dr. Runels: Yes, and Regen, just so you guys know, Regen has a kit that comes with thrombin …

Dr. Edward T: Exactly.

Dr. Runels: … or a way to make thrombin, and they also have a setting on their centrifuge to make a gel. Am I understanding properly? Is that what you’re doing? Are you using that thrombin kit?

Dr. Edward T: That’s exactly what I’m doing, but I’m doing that above the vaginal cuff. When I undock the robot and I’m done with the … Actually, I did the same exact same for a stage IV endometriosis patient today. She’s on the floor. She’s doing great, and after I undocked the robot then I used my PRP kit, and I do a classic O-Shot®, and that’s it.

Dr. Runels: Interesting. Beautiful. That’s pretty amazing combination therapy. Do the people that are getting hysterectomies from you, do they realize what a higher standard that you’re taking this procedure to? I guess they do. Tell it to me more about, do they find that out when they show up for surgery? Are you advertising this combination or way of doing hysterectomy, because it sounds like what I would want my loved one to have?

Dr. Edward T: I think that at the end of the day I’m guided by the same principle that my father, who I operate with still today, actually we just did the case together, has always taught me, which is be very patient centric. I just want to take care of my patients. The money part, and the finances, and the marketing sometimes, as you know, Charles, can get in the way of that.

Dr. Runels: Yes.

2 Guiding Principles That Bring More Patients and Provide Better Care

Dr. Edward T: It’s kind of a very means to an end, I suppose. But, when I start counseling the patients about what we do I start out by saying that we want you to recover as quickly as possible. So, when I lead with that, and I also followup with the fact that we utilize the newest and latest technology in regenerative medicine, the patients begin to understand that their body actually does have a natural mechanism to heal itself. If not using parts of their own body, why would I reach for something on the shelf if I didn’t have to, if I could use their own PRP, and their own thrombin, autologous, to help them heal? I think when it’s set up like that it’s an easy sell.

Dr. Runels: Well, and part of the reason I brought it up was that I feel like, as your father said, Part A is that the want to be patient centric and make sure that we’re always doing the best with the least amount of risk. Then, Part B is that, I think, it’s our responsibility to make sure that our patients know what we’re capable of doing. I think that’s a different way of thinking about it than the way, and I know that’s the way you think, as well, but some people think, “Oh I just want to do it but I don’t want to have to sell it,” but if you use a different way, and it has to be sincere, of course, but if your way is not trying to get people to do things, but your way is taking responsibility for educating people in what you’re able to offer them as an option, and then they decide what they want based on a fully-informed description of the possibilities.

That, I think, is really what we’re supposed to be doing anyway, whether we’re taking insurance or not. If it happens to be something that somebody could pay you for, well that’s wonderful, but it’s kind of what we’re supposed to do anyway, and that is the best way to “sell stuff.” As you know, I never script these conversations with our teachers, because I like the serendipity of discovering along with the people on the call what might be possible. Have you had any of the gynecologists reach out to you, or do they even know it’s a possibility the ones who come to your class for you showing them this way that you’re doing a hysterectomy, or is your description you just gave enough for them to take it and run with it?

Dr. Edward T: Well, I think that they understand it. I always get a very academic nod to what I’m doing but to your point, Charles, some of the GYNs that I train, they’re my colleagues, they’re a little bit slower to adopt, because we’ve been kind of put into a corner with our Board certifications, and you’re supposed to do it this way. I’ll be honest with you, if that’s how we did hormones then we wouldn’t have any progress.

Dr. Runels: Yes.

Dr. Edward T: If all we did was treat to the exact specifications of what [inaudible 00:41:25] put in brackets, none of our patients would feel better. We would still have all these issues.

Dr. Runels: Is there something you can measure, for example, that postop spotting that you were talking about? Is there something you could measure where you could do the next 40 patients, 20 with and 20 without that? It would the great to have some sort of paper where we could let people know what you’re doing. You know, I just put a link in PubMed where there is some discussion already. I couldn’t find the one … There’s one out there somewhere about using PRP as part of the hysterectomy process. I guess it came out of the people who did the research for the last product you mentioned, but I can’t find that paper right now. Anyway, I won’t dwell on it too much, just to let you know it’s something else that would help the whole group, because there’s lots of GYNs and urologists in our group.

Dyspareunia after radiation–Can/How improved with the O-Shot® Procedure

Okay, we’ve got a couple of questions, and I’m going to unmute Stephen Carp who has a question for you. Let’s see if I can unmute him here. Let’s see. I’m just going to let you ask him instead of me trying to slow down the mail. All right. Dr. Carp, you’re unmuted. Go for it.

Dr. Stephen C.: How are you? Good evening.

Dr. Edward T: Hi.

Dr. Stephen C.: I’ve got a patient that came in, been a long-time patient, who came in just looking for a potential solution. Had endometrial cancer. Had a hysterectomy with radiation and has some scarring that’s tender, and discomfort, a few cm proximal to the introitus that’s probably from about 5 to 8 o’clock or so. She came in because she’s actually a physician and wondering if PRP might be something that could help soften that, might help with that area. Have you had any experience with any PRP in post-radiation in the pelvis?

Dr. Edward T: I have not, but when I think about the three or four cases of patients who have had traumatic vaginal deliveries, they create quite a bit of scar tissue in that fourchette. The success cases I’ve had for those particular ones required more than one O-Shot®, and by O-Shot® I mean doing the classic O-Shot®, but then also doing focal 1-2 cc of activated PRP right into that area of the scar tissue to soften it up. I would also go so far as to maybe use vaginal dilators and, depending on the comfort level of the oncologist, there’s a great product that has compounded DHEA that could definitely soften that fourchette. DHEA with history of gynecologic malignancy is still kind of up in the air, but I have a lot of breast cancer survivors. We’re right next to City of Hope, my practice, and we were using a lot of these nontraditional therapies to help these patients out. I can imagine the irradiated tissue is very similar.

Dr. Stephen C.: Yeah, I would think so.

Dr. Runels: Let me add to that in that my position that I am grateful every day is now becoming described in the Earpiece for lots of brilliant people like you guys. I’ve had quite a number of people, probably a dozen different providers, call me and tell me about similar cases, several cases of dyspareunia post radiation. One case in particular comes to mind where a woman had repeated tearing and pain in an old episiotomy scar, and just like you just said, Edward, it took three treatments with injecting, basically infiltrating the areas if you’re getting ready to suture it intra and subdermally with PRP, and then waiting four to six weeks and doing it again, and doing that three times, and then the woman was without pain and without bleeding. It was something that was a nuisance for quite a number of years. Another case of radiation that had some scarring and pain around the anus, as well. Yeah, so it’s been done and it’s been helpful, and hopefully some of you guys will publish a case report.

I had a case ... While we are talking about dyspareunia, I had a case of scleroderma that got well, but just one. These are … No one person has enough to do a series, but maybe we should some case reports, or try to pool it. What else? Anything else, Dr. Carp?

Pelvic Floor Spasm

Dr. Stephen C.: I’ll just as an addition to that, have you had any experience, especially with urogynecologic, with Botox® for the spasms that they get in the pelvic floor?

Dr. Edward T: I have not done that, although many of my colleagues have. One of the risks of doing that is if you do it too much they go into retention. I have not done that particular method. I have used CO2 fractionated laser. I’m a big FemiLift physician. I use FemiLift quite a bit for overactive bladder, as well as the compounded vaginal estrogens work very well. I think there is a great deal of dysfunction at the level of the vaginal epithelium, that thin layer that separates the bladder from the vaginal canal that needs to be addressed. It gets irritated in these patients with overactive bladder.

It’s really interesting, because one of the gold standards that the insurance covers is the administration of Detrol, or an anticholinergic, which many of my patients within about 30-60 days will self-discontinue due to the side effects, the dry mouth, the dry eyes. They might have less overactive bladder but [crosstalk 00:47:28]. There’s some brain slowing, especially in the older population.

Dr. Runels: Yeah, there was actually a paper out about six months ago that was pretty compelling that there really is an increased risk of dementia long term, as well.

Dr. Edward T: I can see why. You, basically, create that parasympathetic overabundance or push the parasympathetic system to try to dry everything out, well it’s probably going to slow your brain function down, as well. The patients are getting forget. I think it’s very high risk in the older population due to polypharmacy.

Dr. Runels: Anything else, Dr. Carp?

Dr. Stephen C.: No. Thank you.

Dr. Runels: Thank you for the excellent question. There was quick question from Dr. Vora about Emsella, and the answer is, “yes,” some of us are combining Emsella with results. Some are using the intensity vibrator that has contraction component to it. Are you doing any of that, Edward?

Dr. Edward T: So, I was using the [Visa 00:48:30] Plus for a while. I don’t know if you’ve seen that as a at-home device.

Dr. Runels: Yes, talk to us about it.

Dr. Edward T: So the Visa Plus is something that the patients were using. They would take home, use as a light therapy that helps with collagen generation and urovascularization. There’s two versions of it. There’s a version that’s available in the United States, and then a stronger version which I think is only available in Canada, is one of the examples of, I think, an at-home treatment that the patients can use.

Patients always want one and done. From the very beginning I try to tell them, especially when it comes to some of the dyspareunia associated with the menopause state, once estrogen runs out and the vaginal epithelium begins to change it takes a variety of different approaches that begins in the office and really continues with the patient at home. I might do an O-Shot® on them and have them go home with something called … There’s a commercially available medication called Intrarosa®, which is compounded DHEA, or I would use vaginal estrogen. They’re going to work on that at home for the next 30 days. They may come back. I do another pelvic exam. Maybe the grade of the atrophy changes, or improves, or they could have one more sexual encounter that month. To me that’s a win. Then we will add a vaginal laser.

The in between treatments, whether it’s a device such as the Visa Plus or these creams are very, very important, whether you’re talking about vaginal health or you’re talking about aesthetics in the face. I think really beginning to set that as a proposition to the patient, “You’re going to be doing things at home, that are going to help.” Certainly having multi-modality.

I have colleagues of mine in Southern California having great success with the Emsella®, to strengthen the pelvic floor, as well as doing an O-Shot®, looking back at our … We have about 300 patients on pellet treatment right now. Many patients will cite that their urinary continence has gotten better within the first treatment of testosterone. How do I know that? It’s because they won’t show up to their urodynamics test, and so I know something is there. Having that multi-modality approach for urinary incontinence, intimacy, even aesthetics I think is going to be key.

A Nine Minute Cram Course on Marketiing Your Mecial Practice, Timeless Intimacy™, and Virtual Assistants from an Engineer/Physician’s Perspective

Dr. Runels: Beautiful. We’re going to talk … We have about nine minutes left and Edward has some interesting ideas about when it comes to marketing with trademarking and not just our procedures but you as a provider and expanding upon that idea. So, we have about eight minutes left, Edward. Before you do that, though, I just want to tell you guys that Edward is, obviously, brilliant and excellent teacher, and excellent as a provider for our procedure, so highly recommend his classes. He’s got one coming up July 27, which is pretty close, but I don’t know if he’s got slots left, but I’ve put a link to that. If he doesn’t have slots in that one I’m sure he has another one coming up soon. With that, Edward, if you don’t mind, talk to us some about, I know you’ve thought a lot about that idea. Can you expand on that some and then we’ll close it down for the night?

Dr. Edward T: Absolutely. So, as I’m going through the mental exercise and thinking about how to combine all the different procedures and finding that a combination of different approaches that hit different aspects of what I’m doing is the best, I really did a deep dive and found that my main focus is intimacy, how to restore it, how to improve it, how to educate patients on it. I was very happy when my trademark, actually I have a copy of it here, by the U.S. Patent Attorney Office was accepted now with for the second year in a row. I’m ready to defend it, because I came up with this idea of Timeless Intimacy. You can see here, this was actually from my-

Dr. Runels: One second. I took the screen back. I’m going to give it back to you. Now you can show us. Go for it.

Dr. Edward T: I applied for a Trademark. It was actually more of an activity than anything else, and it was successfully accepted by the U.S. Patent Attorney Office. This was a recent email, actually July, by my attorney and I was able to submit it again for the second year in a row. The Timeless Intimacy trademark basically encapsulates performing a minimally invasive vaginoplasty, performing an O-Shot® and followed by a laser, in this case a CO2 FemiLift at a particular setting to help heal and to help reconfigure the vaginal vault to take on a more youthful function. I would always tell the patients, if you want a certain tightness or a certain kind of friction coefficient in terms of the sexual intimacy that you were at 21 we’re not going to go past that, right. We want you to be in a place I would say, ideally, between 20 and 30, in a place before you had children, in a place before you entered menopause, such that you could resume intimacy again comfortably and pleasurably with your partner.

As a part of that I then went on to develop Timeless Health Solutions, Inc, which is my Med-Spa or my functional wellness practice. That’s now being developed as its own entity. It has its own collateral. There’s a voice that’s being developed in which the girls in my office are trained to pick up and talk to the patients with a particular voice.

I’m finding who I am as I’m going along in this journey, that originally I started as an engineer. I think I have a very compelling story to use technology and, basically, give that technology and distribute it in such a way to help patients. I’ve become a surgeon in the last few years, a robotic surgeon in the community, helping women have surgery in a minimally invasive way and get back to life sooner, and putting it all together. I think that’s really what the Timeless Experience is. I think it’s really garnered a lot of attention in our community. I know it’s being recognized at the level of [inaudible 00:54:48] hospital systems. I’ve been recently kind of given this idea, this honor, of being a social media expert in women’s health. Now I have this wonderful platform to get all these ideas of regenerative medicine, minimally-invasive surgery, and to be able to talk about intimacy in a way that’s never been done before in my community.

I’ve been very kind of passionate. This was actually what I was going to talk to you about tonight, and I’m going to highly the second point here. I would say, Charles, right now in the last few minutes that I’m in lean startup mode, and I looked at my colleagues, my engineer friends up in Silicon Valley, and there’s this wonderful book by Eric Reese called The Lean Startup. What that means is creating these very small … Let’s see if I have a picture of it. … MVP, that is a minimum viable product, and really getting it out there to see if the population, or the market, is interested in it. What that means for us as busy physicians is before we buy that next laser, or before we buy that next cool sculpting machine, can we create these minimum viable products and test our market, and how convenient is it that our market are the patients who have been following us all this time.

Dr. Runels: Yes. Yes, we already have an audience.

Dr. Edward T: We have a captive audience. In this world of marketing you actually have to pay for these focus groups.

Dr. Runels: Yes, and let me emphasize that real quick. I don’t want to slow down your momentum, but everyone needs to remember, you are marketing to your people. If you [want to 00:56:27] market to the whole world that’s fine, but you need to start with your people. If you don’t have a group of people that you call your people, in my opinion, it’s difficult to have a steady flow. You start by building a fan base of people who love you, because you’ve done good things for you. Now you can do what you’re talking about. Okay, keep going.

Dr. Edward T: I think every once in a while when I get stuck, Charles, I put my engineering hat on and I think about what an engineer would do, because if I think about what a doctor would do, I would probably take on another [inaudible 00:56:58] contract and working harder and I’d probably be- [crosstalk 00:56:59] Just being honest with you. I’ve already seen this. I saw what happened to my father, right? I think desperate times call for desperate innovative measures, and I put my engineering hat on and I found this, and I’m just sharing this with our group, lean startup. In the last minute here I encourage …

Dr. Runels: You know what. Keep going, go a little over. That’s fine. I think this is good stuff.

Dr. Edward T: … and want all of us in the call, the physicians, to really become lean again. I think that all of us as physicians need to find a way that we retract because the environment right not conducive to us expanding aggressively. We must all come together and retract and regroup, much in the way that Sun Tzu says in The Art of War about looking at our enemy and knowing that we are not ready, and we are not powerful enough to be out there and fight. So, we have to retract, and in this very lean startup manner regroup and see what anchors us.

Dr. Runels: Yes.

Dr. Edward T: It’s very easy because all of us in quarter four … I know I’m speaking to everyone on the call right now when the tax comes all of us who are on the call most of us are in private practice, and we are lured by the laser companies, and by a big company to do that capital investment just to decrease our taxable income. Really understand what it is that our market is demanding. We can do that by creating these very small value propositions and testing it. That’s why doing a class on injectables, or learning how to do an O-Shot® is so valuable, because it may be caused that initial fee, the tuition, and that’s it. That fee is the minimal [crosstalk 00:58:47]

Dr. Runels: Then you take the money from that and do the next thing, yes.

Dr. Edward T: You got it, because what makes you think, and forgive me for saying this, that you’re going to be able to make a vaginal laser which can cost up to $100,000 work if the patients in your group don’t even want an O-Shot®? To that same degree, what makes you think buying the newest fractional CO2 facial laser is going to be appropriate when the patients don’t even want you to do a Vampire Facelift® on them?

Dr. Runels: That’s right. The guy who taught me Botox® was doing … He was the top Allergan account in the world, we talked about this before, and he always said, “Get your Botox® practice going then buy the facial laser.” So, exactly that’s the right strategy. When you get to where you’re one or two O-Shots® a week now you can take the money and take the flow, and you know that your laser’s not going to gather dust, or you’re radiofrequency. I’m loving this. Tell us about the next thing on that list.

Dr. Edward T: I guess the next thing, …. Forgive if I’m going over here but-

Dr. Runels: No go for it. We like it.

Dr. Edward T: In addition to retracting … This is what I’ve been doing. I’ve been retracting, rebuilding, regrouping, and creating my brand. The brand tells a strong story that I’m infusing technology with medicine. I actually had a doctor friend of mine, Charles, reach out to me, and she asked me how I’m seven places at once? I said, “What do you mean?” She’s like, “I’m watching your Instagram, man, and you’re like seven places at once. I’m like, “Thank you, I’m not.” I have virtual assistants. I try to automate and eliminate, and I’m doing this because I have a virtual architecture and I check in with this lovely girl in the Philippines. I give her a list of things to do and in the morning it’s all done because of the time zone difference. It could be something as simple as arranging for my dry cleaning, or figuring out a logistical issue for a seminar that I’m going to be teaching out.

But, when I’m able to do that and create that virtual architecture she learns from me. We talk about, as engineers, machine learning, and we talk about artificial intelligence. You don’t really need that when you could actually have bonafide intelligence. These virtual assistants, it’s a skill and I’ll be honest with you, coming out of fellowship I didn’t really know how to manage people that well. I’ve learned more about managing people, and learning how to lead working with these virtual assistants than I have in all the time I’ve graduated, because you learn about time management, because now I know what the value of time is in a quantifiable way. I’ll give you an example.

I found out that it’s actually a lot easier to click with my thumb Expedia and book a flight, and look for a flight than it is to go in almost two hours back and forth in different time zones to get my virtual assistant to book it. That’s a great example, right? But, for something that takes a lot of different steps, like research, I’m trying to find a cheaper way to bring in needles or syringes to my office. That’s an hour affair. I’m putting that to my virtual assistant, so now she does my supply chain and I’m like, “Oh, there’s something called supply chain. Let me learn about how to do supply chain management.” It didn’t cost me that much, and so that becomes part of my virtual architecture. It becomes part of my virtual corporation, my virtual timeless structure, and that’s the virtual architecture that’s rising me, or raising me, to make me look like I’m in seven different places at once. It’s because my virtual architecture is raising me, it’s giving me more time.

Dr. Runels: Beautiful. Both the virtual assistant and someone in the office who functions like an executive assistant, not just doing the nursing work, but they are willing, and expecting to do things like drive your car, or go buy your groceries, that sort of thing, I think when you value your time at at least $1000 an hour, which everyone on this call should be doing, then that person if they save you an hour a day, you can pay them a reasonable rate and still do well. What’s next on that list?

Dr. Edward T: I suppose the last thing … Let me give you the website that I use, and I explore …

Dr. Runels: You can just throw it in chat box and everybody will have it.

Dr. Edward T: It’s onlinejobs.ph. You actually see it.

Dr. Runels: Okay, there you go. Onlinejobs.ph. I concur with you in that the people in the Philippines they like Americans and unless they’re having a typhoon where they lose their internet they are as a rule usually reliable, and they are grateful. You can pay them what for her is not so much, and you can be helping someone have a whole different lifestyle in the Philippines. I highly recommend what you’re doing.

Dr. Edward T: The last part of my pitfall, so I will try to wrap all this up, because between becoming lean, creating a virtual architecture, becoming proficient with all of these advanced regenerative medical procedures, and learning how to do aesthetics with an artful aye, I’ve also learned along the way. A lot of the pitfalls, I think, stem from paid advertising. I think in the group whoever is still listening left, all of us, I think, have all tried to pay-

Dr. Runels: By the way, it’s everybody. Nobody’s dropped off. They’re listening.

Dr. Edward T: Anyone who’s tried to pay for advertising finds it very difficult to measure a return on investment, because in my mind as a physician if I pay for advertising it means that there will a measurable return for a booked and paid patient. However, with marketers and paid advertisers out there, their metric is leads, or …

Dr. Runels: Yes.

Dr. Edward T: … clicker rate. Things that are not as relevant clinically to us and to our bottom line. I think there’s a big discord.

Dr. Runels: They don’t pay the groceries. Clicks don’t pay the groceries do they?

Dr. Edward T: It took me a long time to learn that at the very visceral level, that we have a disconnect here. That disconnect is what’s actually preventing, in my mind, marketers and physicians from really aligning together. I think that if there was a better, more kind of physician-centric way to create paid advertising … You know it’s good that all of us on the call know the basics of marketing and advertising, but the the end of the day we are doing all this to try to get back to what we signed up for, which is to help patients and do medicine.

Dr. Runels: Yes.

Dr. Edward T: As a pitfall I think what I’ve been guilty of is going down too far and kind of veering off course, and there’s so many tools, and so many virtual assistants, and so many Ontraports, and mail … I mean, there’s so many digital pools out there that I think every once in a while I have to pull myself back, not as an engineer now, because that’s all we do is create tools, right, for better solutions, but pull myself back to the medium, which is the physician in me and go back to doing medicine. I would say that’s a pitfall that I’ve realized that it’s very easy to go down that rabbit hole and find that next digital tool, that next widget, that next app, and forget what we kind of signed up for.

Dr. Runels: Just let me expand on that just a little bit and then let’s call it an night. All wonderful stuff, Edward, by the way. There are so many tools, and I’m literally at a class now in Cleveland that cost me 30 grand. I’m in a class today, earlier today, with a guy that made $900,000 in two weeks online. These are high-end people, high-end in that they know how to make money online. It’s interesting, what I’ve noticed is the people who are making 10 million or more on the internet, they’re still doing the basics, and it’s not just online. The other thing that these guys with real businesses with tell you is that you bring it offline as soon as you can. It’s handing out the brochures to your patients, or your just physical card and saying, “Hey, if you know somebody else I can help, would you give this to someone.”

Using the tools, just the basic tools of a video so you don’t have to keep explaining it, emails that you send to your patients every couple weeks so they know that you’re there, that are not fancy, that are messages that give them the things you would say to them if they were in your office anyway about what you want them to do to be healthy, and what you’re able to do for them with explanations and clicks to show them the research. So, a video, a web page that’s helping you let them know what you’re able to do, and then instead of doing all your time marketing you’re doing something, it’s a practice, and so you’re practicing it. But, here’s the fun part, you’re practice of marketing is actually making you a better physician, because you’re teaching your people how to be well leveraging digital tools.

I know if people are on the call that have done it on Instagram and Facebook and all the other tools, and I’m not saying you don’t do those things, but for these procedures what you just said is the formula that works, an email, a video, a web page. Deliver good messages and then while that’s doing you have more time and more money to go take care of your people, sometimes for free because the money’s flowing.

Edward, always a pleasure. I know people, I’m telling you the stick rate was amazing tonight. Everybody was listening, so I know they loved it. One last thing, guys. Edward does a mean class and you can tell he’s on top of all dimensions of this. So, have a great night, and I’m honored always to have your attention. Bye-bye.

Dr. Edward T: Thank you, everyone. Goodnight.

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Q&A. Writing emails, amnion, treating scars, cannulas, loss of sensation.

Relevant links…

Charles Runels: All right so we’ll get started and we’ll go through questions that have been posted on the various websites.

Let’s start with the vampire facelift. By the way, after we finish these questions, I’m going to go over a very quick and easy way to create an email that your patients will love to receive and it will help them both attach to you and want to come see you for the things that you do that will help them. We’ll do that after we cover some of these questions.

We’re on the Vampire Facelift® website. “Hello, does calcium chloride help create better results with vampire hair? Also do you have a contact we can order from? Finally, how much do you mix with the PRP and do you just draw the PRP into a syringe and then draw the calcium chloride up after it, and has it been injected with mix or do you mix it differently?”

I just posted an answer to the activation question. If you go to our company website, cellularmedicineassociation.org, and then you look down here where it says, Questions and Answers activate, and I spent some time right here talking about the different reasons you should and shouldn’t activate, and when you do and you don’t, versus hair versus face, O-shot and P-shot and such. So it’s all right there.

As far as mixing it goes, I like to use a stock bottle so if you have, if you already have plasma in the syringe and you take that syringe and you put a needle on it and you stick the needle into your stock bottle, of course you’ve contaminated your bottle because you put a needle that’s attached to blood on one side in the syringe now into your stock bottle the calcium chloride is in. So I’d pull the calcium chloride out of the stock bottle into a sterile syringe and the pull the PRP up into that syringe that has the calcium chloride in it exactly right when I’m ready to do the procedure because you need to be ready to use it.

Let’s see what else you have. As far as from where can you order it, if you go to our dashboard, you’ll see the dashboard is here. Then if you go to, down here somewhere, it should have where to order everything. Let’s see. That’s all different procedures, ways to do it, well maybe I didn’t put it there so I need to. I get it from Mcguff in California, and I’ll pull it up for you right now. Mcguff compounding pharmacy. There. Mcguffcompoundingpharmacy.com.

So let’s see what other questions we had. On the vampire facelift site. By the way if there are questions from you guys that are attending just push the button and I’ll unmute your mike, the noise gets pretty bad in the background so that’s why I don’t have it unmuted at this point. Lets see, are there frequently asked questions for each procedure that we can use? Where are they located on this site?

So the way I’ve tried to structure … so there’s two sides to the membership sites, or the websites, and they all work the same. There’s one side, so vampirefacelift.com/members, that’s for us. Then vampirefacelift.com with nothing behind it, that’s for the patients. The all have the same format. So there’s O-shot.info, that’s for the patients, there’s oshot.info/members, that is for us.

So when you say frequently asked questions for each procedure that we can use, where are they located, the best place to send people if this is for frequently asked questions by a patient is to send them to the main website. I tried to anticipate the questions. If you look at the number of times this has been edited, you can say, click in here and try to edit the page it will tell you how many times I’ve edited it. It’s probably going to be hundreds of times, we’ll look at it here in a second. But what I do is every time somebody asks a question I try to put it into the website and embed it there so then hopefully they see it. Oh, only 65 times, so of course this is third version of this website but on this particular page only 65 revisions. So those revisions aren’t to make things look pretty, most of the time it’s changing a word, adding a link, you can see there’s a video that needs to be redone. Sometimes something dies. You can see I added a Wikipedia article. I add thins so that every, if someone asks me a question hopefully we anticipate it and hopefully next time they won’t ask that question. So that’s where the frequently asked questions live on the websites.

They’re also put, on most of the websites, on O-Shot®, P-Shot®, I think it’s on the breast lift, you can see I added a review link. Oshot.info/reviews. Here’s a tip right now for getting free advertising, like crazy. I tell people this but still less than a dozen of our providers do it. If you go there to reviews tab, that’s where people ask questions and hen we answer them. Well if you answer a question here, and you can see ,I don’t know I think there’s 300 or so posts or something like that.

So if you go in and you answer, Dr. Posey answered someone’s question right here, then people see that and you can see it links to whenever you answer a question. Whenever you answer a question it links to your profile, so Dr. Seilar answered a question and, from one of the patients, and when you click on it, it takes you to know more about him. There you go, you’re on his website. And when people who go to these pages, they always want to read the reviews, so there’s your way to both find the frequently asked questions and to just throw in a couple of words here and there, taking part of the conversation, and people will see it, they’ll be impressed, and they will come find you. And for some reason, like I said, that’s still very uncommonly done by our people even though it’s a way to get amazing, amazing advertising without really having to do anything as far as money goes.

So here’s another question. Dr. Runels with the current available information, what’s your top PRP harvesting centrifuge in terms of initial cost, for patient cost, ease of use, especially commenting on the clips, insight, [inaudible 00:08:12], TruePRP, they left Harvest out and there are others.

So this technology is changing, the prices are changing and when I look at analysis of the blood itself the numbers are all over the map depending on who paid for the testing. What I can tell you is that I know of failures and, oh they also left region off this list, I know of failures and wild successes with all of the things on that list. My recommendation to you is to get your best price with the best service. If you ask me what’s the best, a Chevrolet or a Ford, I would say that I would never buy a Ford because I had a Ford Pinto when I was 16 and it broke down and so I’m angry at the Ford Motor company since I was 16 years old because they took my money for a lemon. Ford Pinto was the one that would explode when you got hit I the back. But that’s my personal bias, they ripped off a 16 year old boy and I will never forgive them for it.

But maybe you didn’t have that experience, maybe you love Fords, same thing applies to centrifuges. Cut your best deal, all of these kits work, and hopefully our research will show, for example Magellan gives you five times baseline, do you really need that or not? Maybe? Or maybe not. I can give you a more specific thing but it could be out of date by next week so talk to them , cut your best deal.

Let’s see, Thomas asked, do you have any experience using antioxidant serums just afterwards?

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Section 2 of 5 [00:10:00 – 00:20:04](NOTE: speaker names may be different in each section)

Charles Runels: Antioxidant serums just afterwards the Vampire Facelift. The facial or essential oils. I use a HA mist, seems to work well. Sometimes can cause peeling, but not sure if it’s the mist or the facial. What I can tell you, with the facial, whatever you like to use on the face, whether it’s peptide creams … I always like, I’m still an old school 0.1% Retin-A, not Retinol, like Retin-A prescription strength 0.1% cream. Whatever it is that you like, after you do that Vampire Facial, you’ve opened up the skin and you’ve created thousands and thousands of little puncture wounds, so that this material can now be absorbed. So that’s your answer. Whatever you like, use it.

And I find it’s a good time to get people back on a regimen, because they want to protect their investment. It’s like when you check out of Best Buy and they say, “Well do you want the warranty?” Same thing, they’re checking out of their Vampire Facelift, you say, “Well, you really take care of your investment here, and what you’re doing to take care of yourself. We should have you on this, and this, and this.” And I like the Retin-A. And so even if someone has used Retin-A in the past, they may have used it inconsistently, and that motivates them to start using it more consistently.

“Can you give us guidance on hair restoration, and how to know where there are active hair follicles, and where the PRP will work? Is it necessary to do the microneedling?” I don’t think it’s necessary, but I think if you said, “Okay, you have one chance to make this person’s hair grow, and If it doesn’t work we’re going to, I don’t know, run your car off a cliff.” You would probably do everything you know to do, which would include subdermal and microneedling. Doesn’t take that much longer, the cost of goods are reasonable on the expendables for the microneedling device. So I usually do … I do think it’s necessary to do the subdermal, and close behind this on the microneedling, but I always like to do both.

As far as how to know where there’s active hair follicles, you can see where the hair is thin but still present. Obviously you want to treat that. And then there’s this margin where the hair seems to go away. I think it’s worth, if someone has a reasonable hairline, you know, they’re not like a cue ball, if they have a reasonable hairline, I think it’s worth just treating all the way to where the hair line used to be. And I say that because we’ve seen absolutely shocking results in some people where hair grew back where we weren’t expecting it, and others where nothing happened. When I talk to our providers who do hair for a living, they’re hair transplant surgeons, and one guy even wrote textbook on hair … They still can’t tell me how to predict who will respond and who won’t. But the general consensus is to do a series of three, four to six weeks apart. If after the second treatment you see no results, stop, give them their money back, it’s probably not going to work. Thankfully, that’s usually a minority of people.

So, thoughts for using cannulas for PRP. I don’t. And the reason I don’t is when you use a cannula, what do you have to do? You have to make a puncture wound, and then you have to put the cannula through that wound with the idea being now when you extend deeper into the tissue, the cannula avoids further trauma. The thing about PRP, if you’re putting your needle in much further than the puncture wound itself, you’re probably causing unnecessary bruising already, because one of the beauties of PRP that it hydrodissects. You don’t need a needle. For example, with Juvederm, you can’t just inject it and expect it to spread out. It’s going to make a big glob, unless you fan your needle. That’s not so with PRP. You just get the level beneath the dermis and inject, and it just hydrodissects and spreads out as if you were pouring water on the floor. For that reason you don’t need a cannula because when you put the hole through the skin to make the hole for your cannula, that’s as deep as you need to go to inject the PRP, so you don’t really need it. If you like using with a Hyaluronic Acid filler, that’s fine, go for it, but I find it’s about half and half with our providers.

Next question is, “I have a patient with mild acne pitting, with slightly darker skin. Do I set my speed faster and the depth deeper with the microneedling? How many treatments? Expectations?” As far as speed and depth … First of all, with speed. I have a blender that has one switch, on and off, and that’s it. It’s got a steel rod, so I think you can throw nails in there and grind it up. But it has one speed. You’ve seen these blenders that have 16 things: puree, frappe, soupe. How many different words can we use to describe something just spinning around? And it’s bull. Total bull.

I actually talked to the man who invented the Dermapen. And he said they only put three speeds on there because they knew if they didn’t put three speeds, someone else with a pen would brag that they have three speeds. What they found is, as fast as it goes works the best, because you want to make puncture wounds, as many as you can, as fast as you can, to get it over with. So the speed is just whatever you’ve got, plug it in, make sure the battery’s charged if you’re using a battery operated device, and make the depth whatever depth you need to get it to to cause punctate hemorrhaging. Which is going to change, based upon where you are on the face, and whose face your treating.

How many treatments and expectations. Expectations is … That’s like an hour lecture, but as far as if you’re referring to the mild acne itself, then expectations are tremendous. If you do a series of three treatments, six weeks apart, four to six weeks apart, most people are going to love it. So hopefully that answers your question.

Next question, “How do you correct when there is a deep dimple just below the middle of the lip in some patients? Do you use more Juvederm on adjacent sides to get more lift?” A deep dimple just below the middle of the lip in some patients … So, I think I’d need to see a picture, maybe you can post a picture of what you’re thinking about. I hesitate to say much about that without seeing a picture. I will say though, and as a general rule, if someone has a dimple, or a defect, or a pit, or whatever you want to call it, if there’s a place that needs to be filled and it’s deep, as you say here, then I’m probably going to use an HA filler to correct it, and then polish it off with PRP. PRP alone probably won’t work as well, but I guess deep is relative, so to really answer that intelligently I would need to see a photograph.

So I think that’s all of the new questions on the Vampire Facelift, we were a little bit behind on that one. There’s two on the Priapus Shot website. First one says, “I recently attended a Vampire training course in Las Vegas with Dr. Zimmerman, and I had a question about the penis pump. How much pressure? I found that some information says more than 4.5 can damage the penis. I believe that the course recommendation was seven to ten. Do you have any papers that document the most appropriate pressure?” That’s a good question, and I would need to go to the research. The dogma that I’ve heard from urologists and from going on the blogs where the guys … There’s a subculture of people just using penis pumps.

I compare it to what went on back in the ’70s with weight training. I was a teenager in the ’70s and when I went to buy a book on weight training, there was one in the library. And no one knew who Arnold Schwarzenegger was, he was just a weird guy to most people. He was winning these weird contests called Mr. Olympia. And coaches were still telling guys that weight training could make you clumsy. If you go back to the ’60s they recommend to athletes to not lift weights. The point I’m making from all that is there was a subculture. Even physicians came out of this, physicians in the 1980’s

Section 2 of 5 [00:10:00 – 00:20:04]

Section 3 of 5 [00:20:00 – 00:30:04](NOTE: speaker names may be different in each section)

Charles Runels: Even physicians, get a load of this, physicians in the 1980s, late ’80s was the first time that physicians published a paper saying that anabolic steroids actually made you stronger. Up until then, they would say the bodybuilders, that was just water weight. They weren’t really strong. All I have to say, there can be a subculture of people who are basically experimenting on their bodies. You can sometimes be ahead of the physicians about what works, and athletes, especially, are prone to do that. I think, to a certain extent that is happening in the subculture of people who use penis pumps. You can go and find some of those blogs. Like, if you Google, if you Google my name, sovietisms I’ll come up in some of these penis pump blogs. Let’s see if I can find one. If you read the protocols, or following … I’m not saying that’s where we learn how to be … Here we go, the PhalloBoards Penis Enlargement surgery, phalloplasty. This is proboards… phalloplasty.proboards.com. This is all about growing penises. If you go on these blogs, the common dogma seems to be 10 – 20 minutes at a pressure of somewhere seven to ten.

Honestly, I don’t know. I will look at the research and see if I can get you a smarter answer. That’s the number I hear from the urologists and the blogs. More than that, you just create edema, bruising, and you can get damage. Let’s see, what was the other question. All right, let me add to this one other thing that, I know some people use pumps without a pressure gauge. I don’t recommend that because sometimes people, I’ve found, they’ll either pump it up too much, or they will think they’re getting a good pump, and then give them a pump with a gauge on it, they say, “Oh, this is more than 10 [inaudible 00:22:16].” Without that, you really don’t have any objective measurement of what you’re doing. By the way, there was another paper published in The Journal of Sexual Medicine two months ago showing that using a pump, this was in an animal model, we have them with people, but there was another one with an animal model showing that this helps with peyronie’s disease.

Dr. Grow, I have two questions regarding two patients. Patient One, middle-aged man, non-smoker, moderate erectile dysfunction, and he does react to Viagra/Cialis. During intake there seemed to be no psychological etiology. Had a P-Shot two months ago, with [inaudible 00:22:58] PRP, no improvement whatsoever. He said he used the pump daily. So far my patients have always some kind of improvement. This one had none. What is your advice about the P-Shot? Maybe two? What about the cost? Two things I would recommend. First, as far as the cost to the patient, I have … I posted a video about why I always do things for free if they say nothing happened. How I do it, why I do it, but that’s the bottom line. If someone says “Oh, it worked but I want more benefit.” Then I charge them for the next one. If they say “Nothing happened,” then basically, as far as they’re concerned, I stole their money if I stop right there and don’t give their money back, that’s the way I think about it. Maybe it’s not the way you should but it’s what they think. I respect that. As far as I know, anyone who has given me any money, since 2003 when I went to all cash, they either got better and were happy with what it did, or I don’t have their money anymore.

As far as what to do, what else you might do, I do think it’s worth doing this again. I would do it in combination with our whole protocol. If you go to priapusshot.com/peyronies, even though this man doesn’t have peyronie’s disease, the protocol that I put here works for erectile dysfunction as well. For example, using the pump has been shown to help with erectile function. We’ll need less Viagra. Let me add this too. If you go back to think about what we’re doing here, this happened to me once. Someone said “Nothing happened, nothing happened.” So I told my staff and then they delivered that message to me. “Okay, have him come in.” As he was getting on the table to get his repeat Priapus Shot, I said, “Now you’re taking Trimix aren’t you? Have you changed the dose on it?” He said “Yeah, I’ve cut the dose in half.” That’s a win, that is an expected win. If someone’s using Viagra or Cialis, which this man is, it could be that he’s getting the same kind of erection that he did with half the dose of his Viagra or Cialis. That’s the best we can do.

You have to remember to ask them that and also remember to tell them that when you treat them, that we’re not giving you an 18 year old penis, we’re giving you your penis five years ago which is going to be … you’re going to cut your Cialis dose in half or your Trimix, if that’s what you’re using. Anyway, the other things you can do to support it, just like if you had surgery, you have your cholecystectomy and the next day you’re doing LSD, smoking two packs a day and drinking Jack Daniels, you’re probably not going to heal very well. I’m exaggerating obviously but the point I’m making is, there are things you can do to support healing and there are things you can do to interfere with healing. The things that you do that … those things are exactly the things that would support of interfere with platelet rich plasma because we are triggering the healing response.

Here’s the whole protocol for Peyronie’s and for the same thing works for erectile dysfunction. If they’re not on Cialis then I wouldn’t feel the need to start that. But, post prostate surgery and for Peyronie’s disease you might want to because Cialis actually has some biochemical effects that could help prevent the peyronie’s from progressing and cutting off the mechanism might actually help with the reversal of it as well. The research backing all this us is at each link, there’s a video, we’re going to talk about it. You can actually give your people this website, priapus.com/peyronies and suggest that they follow it. I then have sources for them to buy this stuff. On Amazon.

Let’s see, I think there was one more part to that question. I think that’s all that question. Patient number two, who used cocaine and Viagra during his holiday, experienced some kind of pain during sex, ignored it. In the days that followed, sexual sensitivity dropped massively. Urologist and neurologist seen no abnormalities. Neurologist did, actually nothing. The urologist performed an ultrasound. They sent him to a sexology psychotherapist. They could not do anything. According to the patient, there’s no mental cause here, otherwise that, almost never getting erect anymore, which puts a lot of negative pressure on him. The only possibility to get an erection somehow is with tensing his pelvic muscles and straightening his legs. He asked if a P-Shot would help him and how many? I told him I would ask you because of the rapid onset and [inaudible 00:28:40] P-Shot at this kind of onset.

So, if you took out the drug stuff and the story about straightening his legs and tensing his pelvic muscles and standing on one leg and saying three Hail Marys, I would say the next thing I’m about to tell you, I would do. But, with this particular person I would steer clear and just say “I’m not sure if I could help you.” There’s just this red flag feeling when I hear odd things and history of drug use. I’m not saying that this is the most horrible thing and makes people unreliable. Still, cocaine goofs with your ability to have sex. If he’s using cocaine and I give him a P-Shot and six months from now he tells me “My P-Shot’s not working.” Now I have to be the freaking drug police and ask him if he’s still using cocaine. I don’t like to do that. I’ve worked at a drug rehab center, I think I’m good at rehabilitating drug people, very good actually. I don’t like to do it in concert with Priapus Shots. I would want him off of this for a year before I would become his erectile dysfunction-

Section 3 of 5 [00:20:00 – 00:30:04]

Section 4 of 5 [00:30:00 – 00:40:04](NOTE: speaker names may be different in each section)

Charles Runels: Before I would become his erectile dysfunction doctor. But anyway, let’s assume he’s not doing the cocaine and he doesn’t have the story about straightening legs and pelvic muscles and doing three Hail Mary’s to get an erection. In that case, if it were just a history of trauma, and some loss of sensation, I would tell him, lets do two P-Shots, eight weeks apart and not use the pump. For some reason, I’ve found people that have loss of sensation, they do better if you don’t use the pump, if that’s their main thing they’re trying to treat. Not use the pump, two treatments, eight weeks apart and see if he doesn’t get better.

After the second treatment, have him wait a full twelve weeks before we decide if it’s worked or not. So that’s going to be shot, eight weeks, second shot, twelve weeks. So that’s going to be 20 weeks, but these are nerves. They don’t grow like your hair and if you don’t wait that long, you don’t really know what you’ve done so setting that up is to be the deal. I’ll even write it out and have him initial it so he understands what you’re doing. But that’s for people who don’t use cocaine it goofs up your ability to have an erection so I wouldn’t play with it.

O-Shot® with Mid-Urethral Sling

Okay, so those are the two knew ones on Priapus shot. Let’s see there’s … on O-Shot. Here’s the only new one. Dr. Kline said “Can the shot be performed on a patient with a mid-urethral sling in place and if so, does the place of the injection need to be altered or the amount of PRP placed in the urethra?” I actually think, if the shot were done when people do mid-urethral slings, they would probably get better results and more rapid healing. But, we would need someone like Amy Brenner or one of our gynecologists who does slings to tell us the answer to that. I know there was one study done where using the O-Shot in concert with removing mesh gave a really beautiful result and resolved pain. So, the other thing to think about, no matter what the surgery is, say it’s mesh, sling, hysterectomy, all of those things … Well, hysterectomy and mesh, that study’s actually been done. But, one study using PRP with hysterectomy helped healing. I just told you a study taking out mesh helped the pain, helped the healing.

If you’re creating with PRP, something that is normally made with injury to help the healing process, then with any surgery, you can make the argument that using PRP would help the healing process. Therefore, there should be no problem with using it the next day, the next week, the next year. Using PRP should help and there’s no real contra-indication. The only thing is that if I were not the surgeon, I wouldn’t want to be the one doing it post-op until the surgeon released the person and said “Yup, they’re out of the woods, no sign of infection, everything’s working great”, so I don’t get blamed for some post-op complication.

The only other new thing that came up, which I already answered here in words, but the problem is, is amnion stem cells or not? Well, technically, amnionic membrane is a rapidly growing stem cell-like material, but stem cells are alive, or they are just proteins. And the amnion that you’re buying that has been micronized in a syringe or comes as a powder is not living cells. It’s just the amnionic tissue that’s been dehydrated and then Gama radiated and reconstituted so there’s no … Well actually first it’s reconstituted and then Gama radiated, so there’s nothing alive in there. Otherwise you have to worry about catching some disease from the person who contributed the amnion. So there’s no living cells. Now there is [inaudible 00:34:39] who supplies us with the amnion that we sell to our providers as a distributor/wholesaler. They give us a price that’s at the wholesale price. They have a different product that is true, living tissue that is much, much more expensive and it’s not available to us yet. I’m not sure we’ll even need it, but it’s coming. That’s a true living cell. Amnion is not, no matter where you’re getting it.

Now these amino-acid protein chains, or peptide chains, are very, very powerful. That’s the growth hormone, it’s just a peptide chain that codes … You know there’s two types of hormones, there are the steroid-based hormones like testosterone or estrogen that are cholesterol derived. And then there are the peptide chains that are proteins. So that’s why you can’t take insulin by mouth, but you can take [inaudible 00:35:43] by mouth. The acid in your stomach breaks the peptide chains that are in insulin and it just becomes amino acids. As far as your body knows, there’s no difference between eating a hamburger and taking insulin by mouth, because once your body chops all those peptide chains up into individual amino acids, you just have amino acids like in your meal.

But, if you take a steroid like estrogen by mouth, then the acid doesn’t break it apart and it’s absorbed in tact. The point I’m making, is that the peptide chains, even though they’re not alive, they’re very powerful. It’s what’s released from the platelets. So you have peptide chains that are released from platelets, they’re the [inaudible 00:36:35] and all the things that make PRP work. And some of them are exactly the same things made by the pituitary gland, like Somatomedin-C or [inaudible 00:36:41] released from the pituitary gland. Well, growth hormone is released by the pituitary gland and then it causes the tissue in the body, like the liver, to produce Somatomedin-C or [inaudible 00:36:52]. Over two hundred peptide chains are made by the pituitary gland. Over two hundred that we know about so far.

So I think there’s no way to know everything that’s going on when you take these peptide chains from amnion, but what we do know is we have years, much more than with PRP, we have many years of research with amnion showing that these peptide chains have healing properties. I’ve posted some of that research to, I can’t remember which website I put it on now, but I’ll put it here too so it can be found. I think I put it on on the Cellular Medicine, but I recently posted … cellularmedicineassociation.org and then look over the recent post, Amniotic Membrane, Research. So here’s some other papers and actually some of these links open multiple links. So, for example, this one opens multiple papers. Some of these links open ten papers, just with that one link. So that’s some of the relevant research.

Okay. Let’s see what other questions. I think that’s all the new questions on the O-Shot. The Breast Lift, there was one here about sensitivity. “I have a patient that’s had breast implants”, and then after this one I think let’s stop and let me show you a quick, easy way to create an email that’s interesting to your patients and will bring them to you for the things you know how to do. This is one of my hacks, it really kills it. It’s easy, it’s fun, you’ll like it. It makes you smarter. And it brings people to your office.

So, let’s answer this one last question. “I have a patient who had breast implants and has loss of nipple sensitivity. Her primary concern is to regain the sensitivity back. She asks what percentage of people who have received the Vampire Breast Lift do in fact have [inaudible 00:39:03] improvement in sensitivity and are pleased with the results. If you can provide me with an idea of this percentage, that would be helpful.” So, I have had 100% with this. I’ve probably treated, I don’t know, I’ve been doing this fairly regularly for eight years now, and when I’ve surveyed and asked some of our providers on another call what their experience has been, I’ve heard everything from 80% to 90%. I don’t like saying anything is 100%, but for run of the mill, loss of sensitivity for implants or breast feeding, it is very, very, it’s more than 50%, I think is a safe thing to say.

For breast reconstruction post breast cancer, not so good. I don’t even promise them anything. It’s more about aesthetic treatments when I do that.

Okay.

Section 4 of 5 [00:30:00 – 00:40:04]

Section 5 of 5 [00:40:00 – 00:58:14](NOTE: speaker names may be different in each section)

Charles Runels: Okay. I think I’ll show you my little email hack, and then let’s call it a day. So, let’s say … Here’s the process, let me pull this up for you and we’ll [inaudible 00:40:15]. And I’ll just demonstrate it. This is how to write … This is how to write … an email, very quickly, that you people want to read.

Okay, so I first start with what I want to sell. The market, what am I marketing? In other words, let’s say it’s the O-Shot®, as an example. So, I don’t want everybody to come see me for an O-Shot®. All I want to come see me for the O-Shot® are people that I can really help, like if someone’s got … They need a hysterectomy because their cervix is hanging out of their vagina, they don’t need to come see me.

But there are certain things that I do know how to help. So, let’s say that one of them is dyspareunia. So instead of talking about … I always have to think about how to spell that word. So instead of talking about my O-Shot®, why don’t I talk about one of the problems that I do know that I have a high success rate for? Dyspareunia.

Now I know this is like back pain, there’s lots of things that cause dyspareunia. So, we could just pick one of those, but I’m just going to leave it at that for now. We can say dyspareunia post episiotomy, let’s just say dyspareunia. Actually, why don’t we say dyspareunia post-partum. Post-partum, and just make it more fun.

So, this is what I know. Dyspareunia post-partum, we’re the bomb, we’re the O-Shot®. So now, so that’s step one. Number two, and then we’ll just follow this, and I’ll show you how to do this. Literally, five minutes, you’re done with an email. That just kills it.

So number two, you say … okay, so first it’s the what do you want to market? Next, is what problem do you want to solve with the thing you’re marketing? And I’m trying to move this down to number two because that really should be number two. So, make this number two. Ugh, it won’t go. Okay.

So, what problem? Dyspareunia post-partum. Now you’re going to go to PubMed and go to Google, and see, you’re going to find some research. And this is where it gets fun because you should be wanting to read this anyway if you’re treating it. So, let’s just Google it first. We go Dyspareunia post-partum.

I’m telling you, I’m giving you the keys to the kingdom. This works so very, very well. Okay, so definition, not interesting. Okay, this looks like a full text clinical trial that’s underway, but clinical trial’s probably not finished, so … I’d like to find something that’s done.

Okay, episiotomy and the development of post-partum dyspareunia. Done. Apparently, Google likes that. So this will save me from doing the PubMed thing. And let’s just quickly scan it, see what it’s saying. Now here’s the thing. If you have a patient, or if there is someone out there, not even your patient, is dyspareunia post-partum. They can look at this, smart women, they can look at this, figure it out … But even though they’ve figured it out, sort of, they’re not sure if they’ve really figured it out.

And they would love to have a physician think about it with them, and tell them, “Yeah, this is what it means.” And they would even better like it if it’s their physician who’s thinking about it. So, let’s just scan this really quick. Episiotomy, common surgical procedures, a study, episiotomy [inaudible 00:44:11] 39%. [inaudible 00:44:13] sex life, largely unknown. Three months post-partum. More severe dyspareunia … Okay, the aim, assess the impacts, development of post-partum.

So, materials and methods. Let’s just scan it. [inaudible 00:44:32]. Interview, questionnaire, so these are questionnaires, visual analog scales, so we’ll skip down to the results. Of the 200 hundred patients that participated, 100 had vaginal delivery with episiotomy, 100 had C-section all were primigravida. In ages 22-24 years old, okay, characteristics, average incontinent scores, dyspareunia was present. 21% of of group one and 8% in group two. So significant increase in the presence of dyspareunia. So that’s the conclusions right there. Present, not present, so there we go.

So now, situation, whatever [inaudible 00:45:34] dyspareunia. Okay now, here’s how you write the email. Let’s go back to our list, we’re going to need this link right here. So I copy that link to the research and let’s get the numbers down here. Was it 21% versus 8%. Okay. So now, let’s write our email. I like to do Ulyssis, but you can do whatever, I don’t like all the extra stuff in my way when I’m trying to write. So hello, and then you’re going to put first name. Dyspareunia, painful, painful intercourse can put a huge strain on family and relationships. Recent research looked at the percentage of women who suffered with pain after delivery, and found that the percentage jumped from 8%, if there’s a C-section to 21% or about 1 in 5 with vaginal delivery. Now, can you see now you’re talking to your patients like who they are, smart people. And you just learned something. The solutions, my cursor just jumps around, solutions to this problem can be very unsatisfactory. We’ve found that the O-Shot®, procedure can be helpful in most women. Okay. If you know someone who suffers, of course this someone could be the woman reading this, maybe she knows her mother, sister, best friend has problems. If you know someone who suffers with this problem, would you mind letting them know about possibilities of seeing better. I’ll just stop there. Possibilities with the O-Shot®. Sincerely, okay.

Now, you can take this and copy it. However you send your emails, alright, we’re almost done. I don’t know how we’re doing for time here. However you send your emails then. I like using Ontraport.

So you can see I have my contacts sort of sorted out into lots of different categories. For now, you should probably just have one list that your emailing to, but, I have a list of O-Shot® patient inquiries. So about 6,000 people. So we’re gonna send an email to all these people and try to get them to come see you.

So I’m showing you how to write an email. So now selected all those people and this is how you finish off the email. Use [inaudible 00:51:03] contact, whatever you use it will work the same way. So email for me, and then let’s say new, I like to have a promise embedded in the subject, so, 21% of women would be interested in this after childbirth. Okay? Now I take that, what we just copied that we wrote. And again I like using it in whatever your favorite editor is. Now I need to put in the first name and how this works with your software, it’s going to be very similar, but now we need to put the website. So I can say click to read the research. Then you come back up here and find that paper, so back over here, and you just copy that domain name, and then come back to where you’re writing your email, you still with me?

So, click to read the research. I’m showing you how to write something, and the reason people are not going to put this..they’re going to read your emails if you send them emails like this. What I just did was I copied, paste that into that link and I always want it to open up a new window. It’s just a little hack I do to that makes people stay with you.

So they all work the same, they’ll have a little chain link picture, you highlight whatever you want the link to be, then you click on the chain link and you place the domain into the box. And then make the target a new window and then you save it. Alright?

And the we want people to go to the O-Shot® procedure and find you guys, so I am going to the directory for the O-Shot®, O-Shot.info/ actually, I’m just going to put the O-Shot® webpage and then web coach. Now, that’s it. And then you put name, its helpful I think if you have your signature as a picture so you can add your signature in. So, we’ll find my signature, put that in. And even if you have someone else do this, at least if you understand how this can be done you can create the content and have somebody else do this. I think its good to put your phone number and then always put a P.S.

I like putting the little reverse arrows if I want somebody to click on something, because they see that and it slows them down.

Okay, so lets go back and look at what we’ve done. Now I’m going to send it here in a second here in a second and let you see the final. So we first thought of what we’re going to market. Then we decided it was going to be the O-Shot®. And we decided a problem that thing we’re marketing would fix and we picked dyspareunia post-partum. When we googled it we found some research, then, we wrote by an email, just letting people with the problem know about the research and offering your solution, see number 1. So that’s where you put the link. That’s it. Then you send it. Alright so lets go back here, and the other thing before I send it, is I like the text to be at least a font of 16, because people reading this on their Iphone and a lot of them are like me and need reading glasses, they can’t see the little letters. And it’s nice if you put a new picture so people remember what you look like, remember they’re not really thinking about you that much, they’re thinking about their own problems. They don’t really care that much about you. So putting a picture there helps them remember you. And then we send it.

Before I send it I will often make sure to make sure that they do work. So you can see now if I click to read the research it opens a new window, it takes me to that research. And then if I move to the O-Shot® I made that window just taking them there so they will find you and I then I should find the science here and I send them to the research page. Make sure that one works. Yep, were on the research page. So it’s ready to go. And that’s your formula so you go ahead and send it. Hopefully some of these people will actually come see you. So save and send. I think with that we are right at the hour and hopefully you guys got something from the questions and my little tip about how to send out emails to people who actually want to read. Those will rarely go into the spam folder and you’ll get about a 30% opening rate, consistently, if you do what I just taught you. Alright I guess that’s it. Let me see if there are any questions and we’ll shut this down. None? I don’t see any questions so thank-you guys, you guys have a good week and I’ll post a recording to this to the CMA website.

Section 5 of 5 [00:40:00 – 00:58:14]